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Article

A role for Ctr9p and Paf1p in the regulation G1 cyclin expression in yeast.

Nucleic acids research - 15 May 1999

Koch C, Wollmann P, Dahl M, Lottspeich F

Abstract excerpt

Entry into the cell cycle in budding yeast involves transcriptional activation of G1cyclin genes and DNA synthesis genes when cells reach a critical size in late G1. Expression of G1cyclins CLN1 and CLN2 is regulated by the transcription factor SBF (composed of Swi4p and Swi6p) and depends on the cyclin-dependent Cdc28 protein kinase and cyclin Cln3p. To identify novel regulators of SBF-dependent gene expression...

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Source

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Identifiers

PMID: 10219085
DOI: 10.1093/nar/27.10.2126
PMCID: PMC148432

Genes

CTR9
TPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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A role for Ctr9p and Paf1p in the regulation G1 cyclin expression in yeast.PMID 10219085Read ↗

Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex.Semantic proximity Read ↗

The transcription factor Swi5 regulates expression of the cyclin kinase inhibitor p40SIC1.Semantic proximity Read ↗

PP2ARts1 is a master regulator of pathways that control cell size.Semantic proximity Read ↗

Genetic interactions with CLF1 identify additional pre-mRNA splicing factors and a link between activators of yeast vesicular transport and splicing.Semantic proximity Read ↗

Evidence that the pre-mRNA splicing factor Clf1p plays a role in DNA replication in Saccharomyces cerevisiae.Semantic proximity Read ↗

Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins.Semantic proximity Read ↗

Phenotypic analysis of Paf1/RNA polymerase II complex mutations reveals connections to cell cycle regulation, protein synthesis, and lipid and nucleic acid metabolism.Semantic proximity Read ↗

Activation of CLN1 and CLN2 G1 cyclin gene expression by BCK2.Semantic proximity Read ↗

Cytoplasmic poly(A) polymerases mediate cellular responses to S phase arrest.Semantic proximity Read ↗

The G(1) cyclin Cln3 promotes cell cycle entry via the transcription factor Swi6.Semantic proximity Read ↗

The Paf1 complex has functions independent of actively transcribing RNA polymerase II.Semantic proximity Read ↗

The Saccharomyces cerevisiae NPS1 gene, a novel CDC gene which encodes a 160 kDa nuclear protein involved in G2 phase control.Semantic proximity Read ↗

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