Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Significance of p53 expression in immature teratomas.

Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society - 1 Jan 2000

Charoenkwan Pimlak, Senger Christof, Weitzman Sheila, Sexsmith Elizabeth, Sherman Christopher G, Malkin David, Thorner Paul S

Abstract excerpt

Twenty-nine pediatric immature teratomas were reviewed to determine the frequency and clinical significance of p53 expression. Tumors were stained for p53 expression by immunohistochemistry and results were correlated with the presence of other germ cell tumor elements and with outcome. Sequencing of p53 for mutations was performed on positive cases. Eighteen cases showed widespread positive p53 staining of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclin-Dependent Kinase Inhibitor p21
Share to Cyclins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoenzyme Techniques

Share to Neoplasm Recurrence, Local

Share to Polymorphism, Single-Stranded Conformational

Share to Proto-Oncogene Proteins c-bcl-2

Share to Teratoma

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 12202994
DOI: 10.1007/s10024-001-0268-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Significance of p53 expression in immature teratomas.PMID 12202994Read ↗

Elevated p53 protein expression; a predictor of relapse in rare chronic myeloid malignancies in children?Semantic proximity Read ↗

Immunohistochemical detection of p53 in Wilms' tumors correlates with unfavorable outcome.Semantic proximity Read ↗

Universal poor survival in children with medulloblastoma harboring somatic TP53 mutations.Semantic proximity Read ↗

Infrequent mutation of the p53 gene in fibrous tumors of infancy and childhood.Semantic proximity Read ↗

Bax mutation and overexpression inversely correlate with immature phenotype and prognosis of childhood germ cell tumors.Semantic proximity Read ↗

Immunohistochemical detection of p63 in testicular germ cell neoplasia.Semantic proximity Read ↗

Expression of p53 and prognosis in children with malignant gliomas.Semantic proximity Read ↗

Expression of p53 protein in T- and natural killer-cell lymphomas is associated with some clinicopathologic entities but rarely related to p53 mutations.Semantic proximity Read ↗

Overexpression of p53 and rare genetic mutation in mesenchymal chondrosarcoma.Semantic proximity Read ↗

Immunohistochemical detection of p53 protein expression in various childhood astrocytoma subtypes: significance in tumor progression.Semantic proximity Read ↗

Results of p53 analysis in pediatric malignancies in Poland.Semantic proximity Read ↗

p53 protein alterations in human testicular cancer including pre-invasive intratubular germ-cell neoplasia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.