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Article

Expression of p53 and prognosis in children with malignant gliomas.

The New England journal of medicine - 7 Feb 2002

Pollack Ian F, Finkelstein Sydney D, Woods Jeffrey, Burnham Judith, Holmes Emiko J, Hamilton Ronald L, Yates Allan J, Boyett James M, Finlay Jonathan L, Sposto Richard

Abstract excerpt

BACKGROUND: The prognosis of children with high-grade gliomas is uncertain, even when clinical and histologic findings are considered. We investigated whether mutations in the TP53 gene or the degree of expression of p53 protein in high-grade gliomas is associated with progression-free survival in children with these tumors. METHODS: Paraffin-embedded specimens of malignant gliomas from children treated in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11832530
DOI: 10.1056/NEJMoa012224

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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