Article
Universal poor survival in children with medulloblastoma harboring somatic TP53 mutations.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Mar 2010
Tabori Uri, Baskin Berivan, Shago Mary, Alon Noa, Taylor Michael D, Ray Peter N, Bouffet Eric, Malkin David, Hawkins Cynthia
Abstract excerpt
PURPOSE: Medulloblastoma is the prototype of treatment success in modern pediatric neuro-oncology. Unfortunately, 20% to 30% of tumors recur despite maximal resection and multimodal therapy. Multiple biologic prognostic markers have been investigated to predict recurrences, but controversy remain...
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