Article
A approximately 35 kDa polypeptide from insect cells binds to yeast ACS like elements in the presence of ATP.
BMC biochemistry - 19 Aug 2002
Dhar Suman K, Mondal Neelima, Soni Rajesh K, Mukhopadhyay Gauranga
Abstract excerpt
BACKGROUND: The S. cerevisiae origin recognition complex binds to the ARS consensus sequence in an ATP dependent fashion. Recently, the yeast Cdc6 has been reported to have DNA binding activity. Conservation of replication proteins among different species strongly supports their functional similarity. Here we report the results of an investigation into the DNA binding activity of human Cdc6 protein. Cdc6 was...
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