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Article

Role for a Xenopus Orc2-related protein in controlling DNA replication.

Nature - 25 Jan 1996

Carpenter P B, Mueller P R, Dunphy W G

Abstract excerpt

The six-subunit origin recognition complex (ORC) is essential for the initiation of DNA replication at specific origins in the budding yeast Saccharomyces cerevisiae. An important issue is whether DNA replication in higher eukaryotes, in which the characteristics of replication origins are poorly defined, occurs by an ORC-dependent mechanism. We have identified a Xenopus laevis Orc2-related protein (XORC2) by its...

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Source

Identifiers

PMID: 8552193
DOI: 10.1038/379357a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role for a Xenopus Orc2-related protein in controlling DNA replication.PMID 8552193Read ↗

Interaction of Cdc2 and Cdc18 with a fission yeast ORC2-like protein.Semantic proximity Read ↗

Characterization of an essential Orc2p-associated factor that plays a role in DNA replication.Semantic proximity Read ↗

The origin recognition complex has essential functions in transcriptional silencing and chromosomal replication.Semantic proximity Read ↗

Schizosaccharomyces pombe Orc5 plays multiple roles in the maintenance of genome stability throughout the cell cycle.Semantic proximity Read ↗

The origin recognition complex is dispensable for endoreplication in Drosophila.Semantic proximity Read ↗

Replication licensing regulated by a short linear motif within an intrinsically disordered region of origin recognition complex.Semantic proximity Read ↗

Factors affecting the diversity of DNA replication licensing control in eukaryotes.Semantic proximity Read ↗

Orc6 involved in DNA replication, chromosome segregation, and cytokinesis.Semantic proximity Read ↗

Orc mutants arrest in metaphase with abnormally condensed chromosomes.Semantic proximity Read ↗

A WD-repeat protein stabilizes ORC binding to chromatin.Semantic proximity Read ↗

Functional analysis of an Orc6 mutant in Drosophila.Semantic proximity Read ↗

An Essential and Cell-Cycle-Dependent ORC Dimerization Cycle Regulates Eukaryotic Chromosomal DNA Replication.Semantic proximity Read ↗

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