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Article

Clustered adenine/thymine stretches are essential for function of a fission yeast replication origin.

Molecular and cellular biology - 1 Oct 1999

Okuno Y, Satoh H, Sekiguchi M, Masukata H

Abstract excerpt

We have determined functional elements required for autonomous replication of the Schizosaccharomyces pombe ars2004 that acts as an intrinsic chromosomal replication origin. Internal deletion analysis of a 940-bp fragment (ars2004M) showed three regions, I to III, to be required for autonomously replicating sequence (ARS) activity. Eight-base-pair substitutions in the 40-bp region I, composed of arrays of...

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Identifiers

PMID: 10490609
DOI: 10.1128/MCB.19.10.6699
PMCID: PMC84658

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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