Article
High-throughput loss of heterozygosity mapping in 26 commonly deleted regions in breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2003
Ellsworth Rachel E, Ellsworth Darrell L, Lubert Susan M, Hooke Jeff, Somiari Richard I, Shriver Craig D
Abstract excerpt
Capillary array electrophoresis and laser-assisted microdissection, which provide increased speed and accuracy in loss of heterozygosity studies, are often used independently in studying breast cancer; the successful coupling of these emerging technologies, however, must overcome technical problems, especially those related to the poor quality and quality of DNA typically retrieved from archival tumor samples....
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