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Article

Disease severity in Danish multiple sclerosis patients evaluated by MRI and three genetic markers (HLA-DRB1*1501, CCR5 deletion mutation, apolipoprotein E).

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Aug 2002

Schreiber K, Otura A B, Ryder L P, Madsen H O, Jørgensen O S, Svejgaard A, Sorensen P S

Abstract excerpt

As the understanding of the autoimmune inflammatory response in multiple sclerosis (MS) expands, polymorphic genes involved in this process become possible candidates that may determine the severity of disease. Therefore, three candidate genes DRB1*1501, CCR5 and apolipoprotein E (APOE) were examined in a population-based patient sample (n = 70) to assess an association between disease progression measured by...

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Source

Identifiers

PMID: 12166499
DOI: 10.1191/1352458502ms816oa

Genes

APOE
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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