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Article

Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies

1 Aug 2016

Abstract excerpt

OBJECTIVE: We investigated the association between 52 risk variants identified through genome-wide association studies and disease severity in multiple sclerosis (MS). METHODS: Ten unique MS case data sets were analyzed. The Multiple Sclerosis Severity Score (MSSS) was calculated using the Expanded Disability Status Scale at study entry and disease duration. MSSS was considered as a continuous variable and as 2...

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PMID: 27540591
DOI: 10.1212/nxg.0000000000000087

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