Article
Estimation of sib-pair IBD sharing and multipoint polymorphism information content by linear regression.
Behavior genetics - 1 May 2002
Rijsdijk Frühling V, Sham Pak C
Abstract excerpt
A simple method of estimating IBD sharing (pi) of sibling pairs from multipoint genotype data based on linear regression is presented. The new method is an extension of that developed by Fulker, Cherny, and Cardon (1995) and involves a measure of sib-pair specific information, W, defined as the difference between the unconditional variance of pi and the conditional variance of pi given the marker genotype data....
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