Article
Multipoint estimation of identity-by-descent probabilities at arbitrary positions among marker loci on general pedigrees.
Human heredity - 1 Jan 2001
Sobel E, Sengul H, Weeks D E
Abstract excerpt
OBJECTIVES: To describe, implement, and test an efficient algorithm to obtain multipoint identity-by-descent (IBD) probabilities at arbitrary positions among marker loci for general pedigrees. Unlike existing programs, our algorithm can analyze data sets with large numbers of people and markers. The algorithm has been implemented in the SimWalk2 computer package. METHODS: Using a rigorous testing regimen...
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