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Article

Glucocorticoid receptor variants: clinical implications.

The Journal of steroid biochemistry and molecular biology - 1 Jun 2002

DeRijk R H, Schaaf M, de Kloet E R

Abstract excerpt

Following exposure to stress, cortisol is secreted from the adrenal cortex under the control of the hypothalamic-pituitary-adrenal axis (HPA-axis). Central in the regulation of the HPA-axis is a two tied corticosteroid-receptor system, comprised of high and low affinity receptors, the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR), respectively. In addition, these corticosteroid receptors...

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PMID: 12137800
DOI: 10.1016/s0960-0760(02)00062-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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