Corticosteroid receptor genetic polymorphisms and stress responsivity.

doi:10.1385/ENDO:28:3:263

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Article

Corticosteroid receptor genetic polymorphisms and stress responsivity.

Endocrine - 1 Dec 2005

DeRijk Roel, de Kloet E Ronald

Abstract excerpt

A fundamental question in the neuroendocrinology of stress-related psychopathology is why some individuals flourish and others perish under similar adverse conditions. In this contribution we focus on the variants of mineralocorticorticoid (MR) and glucocorticoid receptors (GR) that operate in balance and coordinate behavioral, autonomic, and neuroendocrine response patterns involved in homeostasis and health. In...

Topics

Adaptation, Physiological
Humans
Hydrocortisone
Polymorphism, Single Nucleotide
Receptors, Glucocorticoid
Receptors, Mineralocorticoid
Stress, Physiological
Stress, Psychological

Source

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Identifiers

PMID: 16388115
DOI: 10.1385/ENDO:28:3:263

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