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Article

Metastable epialleles in mammals.

Trends in genetics : TIG - 1 Jul 2002

Rakyan Vardhman K, Blewitt Marnie E, Druker Riki, Preis Jost I, Whitelaw Emma

Abstract excerpt

There are some mammalian alleles that display the unusual characteristic of variable expressivity in the absence of genetic heterogeneity. It has recently become evident that this is because the activity of these alleles is dependent on their epigenetic state. Interestingly, the epigenetic state is somewhat labile, resulting in phenotypic mosaicism between cells (variegation) and also between individuals...

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PMID: 12127774
DOI: 10.1016/s0168-9525(02)02709-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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