Article
Genome-wide linkage analysis for celiac disease in North American families.
American journal of medical genetics - 22 Jul 2002
Neuhausen Susan L, Feolo Mike, Camp Nicola J, Farnham James, Book Linda, Zone John J
Abstract excerpt
Celiac disease (CD) is an autoimmune disease caused by sensitivity to the dietary protein gluten. It has a prevalence of 1 in 250 in the United States. Multiple-case families are common with a risk to siblings from 10-12%. Previous linkage studies have found no significant evidence for linkage other than to HLA. In this study, we performed a genome-wide search on 62 families with at least two cases of CD to...
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