Article
Celiac disease genetics: past, present and future challenges.
Journal of pediatric gastroenterology and nutrition - 1 Jul 2014
Wijmenga Cisca, Gutierrez-Achury Javier
Abstract excerpt
In the past few years there has been enormous progress in unraveling the genetic basis of celiac disease (CD). Apart from the well-known association to HLA, there are currently 40 genomic loci associated to CD. Most of these loci show pleiotropic effects across many autoimmune diseases and highlight the importance of a dysregulated immune system in the predisposition to CD. It is still too early, however, to use...
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