Article
Celiac disease: moving from genetic associations to causal variants.
Clinical genetics - 1 Sept 2011
Hrdlickova B, Westra H-J, Franke L, Wijmenga C
Abstract excerpt
Genome-wide association studies are providing insight into the genetic basis of common complex diseases: more than 1150 genetic loci [2165 unique single nucleotide polymorphisms (SNPs)] have recently been associated to 159 complex diseases. The hunt for genes contributing to immune-related diseases has been particularly successful in celiac disease, for example, with 27 genome-wide significantly associated loci...
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