Article
Genome-wide linkage analysis of Scandinavian affected sib-pairs supports presence of susceptibility loci for celiac disease on chromosomes 5 and 11.
European journal of human genetics : EJHG - 1 Dec 2001
Naluai A T, Nilsson S, Gudjónsdóttir A H, Louka A S, Ascher H, Ek J, Hallberg B, Samuelsson L, Kristiansson B, Martinsson T, Nerman O, Sollid L M, Wahlström J
Abstract excerpt
Celiac disease (CD) is a common chronic inflammatory disorder of the small intestine with a multifactorial aetiology. HLA is a well-known risk factor, but other genetic factors also influence disease susceptibility. To identify the genes involved in this disorder, we performed a genome-wide scan on 106 well-defined Swedish and Norwegian families with at least two affected siblings. We investigated familial...
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