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Article

Replication of celiac disease UK genome-wide association study results in a US population.

Human molecular genetics - 1 Nov 2009

Garner C P, Murray J A, Ding Y C, Tien Z, van Heel D A, Neuhausen S L

Abstract excerpt

Celiac disease is a common disease with a prevalence of approximately 1%. A recent genome-wide association study (GWAS) and follow-up study identified eight loci significantly associated with celiac disease risk. We genotyped the top 1020 non-HLA single nucleotide polymorphisms (SNPs) from the GWAS study that were genotyped in the previous follow-up study. After quality control assessments, 975 SNPs were analyzed...

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Identifiers

PMID: 19648293
DOI: 10.1093/hmg/ddp364
PMCID: PMC2758145

Genes

ITGA4
LPP

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