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Article

Association analysis of the extended MHC region in celiac disease implicates multiple independent susceptibility loci.

PloS one - 1 Jan 2012

Ahn Richard, Ding Yuan Chun, Murray Joseph, Fasano Alessio, Green Peter H R, Neuhausen Susan L, Garner Chad

Abstract excerpt

Celiac disease is a common autoimmune disease caused by sensitivity to the dietary protein gluten. Forty loci have been implicated in the disease. All disease loci have been characterized as low-penetrance, with the exception of the high-risk genotypes in the HLA-DQA1 and HLA-DQB1 genes, which are necessary but not sufficient to cause the disease. The very strong effects from the known HLA loci and the...

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Identifiers

PMID: 22615847
DOI: 10.1371/journal.pone.0036926
PMCID: PMC3355177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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