Article
Relationship of the delta-opioid receptor gene to heroin abuse in a large Chinese case/control sample.
American journal of medical genetics - 1 Jun 2002
Xu Ke, Liu Xie-he, Nagarajan Saumya, Gu Xiao-Yong, Goldman David
Abstract excerpt
Pharmacological and electrophysiological evidence has shown that opioid receptors are involved in the mechanism of heroin dependence. Thus, opioid receptors are appropriate candidate genes for case-control association studies of heroin dependence. Previously, two single nucleotide polymorphisms (SNPs), OPRD1 921T > C and 80G > T, of the human delta opioid receptor gene were used in population-based studies of...
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