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Article

Association between dopamine D2 receptor gene polymorphisms and the risk of heroin dependence.

Genetics and molecular research : GMR - 3 Nov 2016

Wang N, Zhang J B, Zhao J, Cai X T, Zhu Y S, Li S B

Abstract excerpt

Heroin dependence is a chronic relapsing brain disease. Researchers have reported that the dopamine D2 receptor (DRD2) is involved in the development of opiate dependence. To identify markers that contribute to the genetic susceptibility to heroin addiction, we examined the potential association between heroin dependence and six polymorphisms of the DRD2 gene using the MassARRAY system. Three hundred and...

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Identifiers

PMID: 27819741
DOI: 10.4238/gmr15048772

Genes

DRD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association between dopamine D2 receptor gene polymorphisms and the risk of heroin dependence.PMID 27819741Read ↗

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The ADH1B and DRD2 gene polymorphism may modify the protective effect of the ALDH2 gene against heroin dependence.Semantic proximity Read ↗

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