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Article

Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence.

Drug and alcohol dependence - 1 Nov 2016

Randesi Matthew, van den Brink Wim, Levran Orna, Blanken Peter, Butelman Eduardo R, Yuferov Vadim, da Rosa Joel Correa, Ott Jurg, van Ree Jan M, Kreek Mary Jeanne

Abstract excerpt

BACKGROUND: Heroin addiction is a chronic, relapsing brain disease. Genetic factors are involved in the development of drug addiction. The aim of this study was to determine whether specific variants in genes of the opioid system are associated with non-dependent opioid use and heroin dependence. METHODS: Genetic information from four subject groups was collected: non-dependent opioid users (NOD) [n=163];...

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Share to Analgesics, Opioid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Protein Precursors

Share to Receptors, Opioid

Share to Receptors, Opioid, delta

Source

Open in PubMed Open full text

Identifiers

PMID: 27664554
DOI: 10.1016/j.drugalcdep.2016.08.634
PMCID: PMC6842569

Genes

OPRD1
PNOC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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