Article
Human delta-opioid receptor gene and susceptibility to heroin and alcohol dependence.
American journal of medical genetics - 15 Oct 1999
Franke P, Nöthen M M, Wang T, Neidt H, Knapp M, Lichtermann D, Weiffenbach O, Mayer P, Höllt V, Propping P, Maier W
Abstract excerpt
In the present study, we tested the hypothesis that addictive behavior may be influenced by genetic variation in the human delta-opioid receptor gene. We investigated the contribution of a silent T to C change in the coding region to the development of heroin and alcohol dependence using large case-control and family-based association samples. Presence of the C allele was previously reported to significantly...
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