Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An analysis of genetic association in opioid dependence susceptibility.

Journal of clinical pharmacy and therapeutics - 1 Feb 2018

Nagaya D, Zahari Z, Saleem M, Yahaya B H, Tan S C, Yusoff N M

Abstract excerpt

WHAT IS KNOWN: Drug addiction is a novelty-seeking personality trait that is associated with the candidate genes OPRD1 (opioid delta receptors), OPRK1 (opioid kappa receptors) and PDYN (prodynorphin). However, associations between single nucleotide polymorphisms (SNPs) rs1042114 (80G>T) of the OPRD1 gene, rs702764 (843 A>G) of the OPRK1 gene, and rs910080 (3' UTR _743T>C), rs1997794 (5' UTR -381A>G) and rs1022563...

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Gene Frequency
Share to Genetic Predisposition to Disease
Share to Genotype
Share to Opioid-Related Disorders
Share to Polymorphism, Single Nucleotide
Share to Receptors, Opioid, delta
Share to Receptors, Opioid, kappa

Source

Identifiers

PMID: 28656735
DOI: 10.1111/jcpt.12585

Genes

OPRD1
OPRK1
PDYN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An analysis of genetic association in opioid dependence susceptibility.PMID 28656735Read ↗

Association of OPRD1 Gene Variants with Opioid Dependence in Addicted Male Individuals Undergoing Methadone Treatment in the North of IranSemantic proximity Read ↗

Epistatic effects between variants of kappa-opioid receptor gene and A118G of mu-opioid receptor gene increase susceptibility to addiction in Indian population.Semantic proximity Read ↗

A brief review of the genetics and pharmacogenetics of opioid use disorders.Semantic proximity Read ↗

Genetic susceptibility of opioid receptor genes polymorphism to drug addiction: A candidate-gene association study.Semantic proximity Read ↗

Genetic and Epigenetic Approaches to Opioid Use Disorder.Semantic proximity Read ↗

A118G mu opioid receptor polymorphism among drug addicts in Malaysia.Semantic proximity Read ↗

Genetic Variants Linked to Opioid Addiction: A Genome-Wide Association Study.Semantic proximity Read ↗

Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence.Semantic proximity Read ↗

Genetic Variants Linked to Opioid Addiction: A Genome Wide Association StudySemantic proximity Read ↗

Association Study of Opioid Receptor Delta-Type 1 (OPRD1) Gene Variants with Nicotine Dependence in an Iranian Population.Semantic proximity Read ↗

OPRD1 Genetic Variation and Human Disease.Semantic proximity Read ↗

Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.