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Article

Association of OPRD1 polymorphisms with heroin dependence in a large case-control series.

Addiction biology - 1 Jan 2014

Nelson Elliot C, Lynskey Michael T, Heath Andrew C, Wray Naomi, Agrawal Arpana, Shand Fiona L, Henders Anjali K, Wallace Leanne, Todorov Alexandre A, Schrage Andrew J, Madden Pamela A F, Degenhardt Louisa, Martin Nicholas G, Montgomery Grant W

Abstract excerpt

Genes encoding the opioid receptors (OPRM1, OPRD1 and OPRK1) are obvious candidates for involvement in risk for heroin dependence. Prior association studies commonly had samples of modest size, included limited single nucleotide polymorphism (SNP) coverage of these genes and yielded inconsistent results. Participants for the current investigation included 1459 heroin-dependent cases ascertained from maintenance...

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Source

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Identifiers

PMID: 22500942
DOI: 10.1111/j.1369-1600.2012.00445.x
PMCID: PMC3867542

Genes

OPRD1
OPRK1
OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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