Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms in the opioid receptor delta 1 (OPRD1) gene are associated with methadone dose in methadone maintenance treatment for heroin dependence.

Journal of human genetics - 1 Apr 2020

Fang Chiu-Ping, Wang Sheng-Chang, Tsou Hsiao-Hui, Chung Ren-Hua, Hsu Ya-Ting, Liu Shu Chih, Kuo Hsiang-Wei, Liu Tung-Hsia, Chen Andrew C H, Liu Yu-Li

Abstract excerpt

Delta opioid receptor (DOR) is well known to be involved in heroin dependence. This study tested the hypothesis that single nucleotide polymorphisms (SNPs) in the opioid receptor delta 1 (OPRD1) gene coding region are associated with treatment responses in a methadone maintenance therapy (MMT) cohort in Taiwan. Three hundred forty-four MMT patients were recruited. Diastolic/systolic blood pressure, heart rate,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Heroin Dependence
Share to Methadone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Receptors, Opioid, delta

Source

Identifiers

PMID: 31907389
DOI: 10.1038/s10038-019-0718-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms in the opioid receptor delta 1 (OPRD1) gene are associated with methadone dose in methadone maintenance treatment for heroin dependence.PMID 31907389Read ↗

Genetic polymorphisms in the opioid receptor mu1 gene are associated with changes in libido and insomnia in methadone maintenance patients.Semantic proximity Read ↗

Association of OPRD1 Gene Variants with Opioid Dependence in Addicted Male Individuals Undergoing Methadone Treatment in the North of IranSemantic proximity Read ↗

κ Opioid Receptor 1 Single Nucleotide Polymorphisms were Associated with the Methadone Dosage.Semantic proximity Read ↗

The impact of OPRM1's genetic polymorphisms on methadone maintenance treatment in opioid addicts: a systematic review.Semantic proximity Read ↗

Contribution of Genetic Polymorphisms and Haplotypes in DRD2, BDNF, and Opioid Receptors to Heroin Dependence and Endophenotypes Among the Han Chinese.Semantic proximity Read ↗

OPRM1 genetic polymorphisms are associated with the plasma nicotine metabolite cotinine concentration in methadone maintenance patients: a cross sectional study.Semantic proximity Read ↗

A single nucleotide polymorphism in OPRM1(rs483481) and risk for heroin use disorder.Semantic proximity Read ↗

Pharmacogenetic study of methadone treatment for heroin addiction: associations between drug-metabolizing gene polymorphisms and treatment efficacy.Semantic proximity Read ↗

Association of the D-amino acid oxidase gene with methadone dose in heroin dependent patients under methadone maintenance treatment.Semantic proximity Read ↗

Impact of SNP-SNP interaction among ABCB1, ARRB2, DRD1 and OPRD1 on methadone dosage requirement in Han Chinese patients.Semantic proximity Read ↗

ABCB1, SLC22A1, COMT, and OPRM1 genotypes: Study of their influence on plasma methadone levels and clinical response to methadone maintenance treatment in opioid use disorder.Semantic proximity Read ↗

Variants of opioid system genes are associated with non-dependent opioid use and heroin dependence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.