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Article

Typhlocolitis in NF-kappa B-deficient mice.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2001

Erdman S, Fox J G, Dangler C A, Feldman D, Horwitz B H

Abstract excerpt

Activation of inflammatory gene expression by the transcription factor NF-kappaB is a central pathway in many inflammatory disorders, including colitis. Increased NF-kappaB activity has been linked with development of colitis in humans and animal models, thus it was unexpected when NF-kappaB-deficient mice developed spontaneous typhlocolitis. To further characterize this finding, we induced typhlocolitis in...

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Identifiers

PMID: 11160181
DOI: 10.4049/jimmunol.166.3.1443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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