Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Normal Liver Regeneration in P50/Nuclear Factor κB1 Knockout Mice

1 Apr 2001

Abstract excerpt

Nuclear factor kappaB (NF-kappaB) is rapidly activated during liver regeneration following partial hepatectomy or carbon tetrachloride (CCl(4))-mediated liver injury and is felt to be important in the antiapoptotic and regenerative responses. After partial hepatectomy, livers of mice deficient in the p50 subunit of NF-kappaB (p50(-/-)) showed a loss of NF-kappaB and decreased STAT3 transcription factor DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endoplasmic Reticulum Stress and Disease
Share to Liver physiology and pathology
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11283856
DOI: 10.1053/jhep.2001.23192

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Normal Liver Regeneration in P50/Nuclear Factor κB1 Knockout MicePMID 11283856Read ↗

Nuclear factor-kappaB1 (p50) limits the inflammatory and fibrogenic responses to chronic injury.Semantic proximity Read ↗

Gene deletion of NF-kappa B p50 does not alter the hepatic inflammatory response to ischemia/reperfusion.Semantic proximity Read ↗

Role of nuclear factor κB in liver health and diseaseSemantic proximity Read ↗

Conditional deletion of beta-catenin reveals its role in liver growth and regeneration.Semantic proximity Read ↗

Nuclear factor-kappa B plays a central role in tumour necrosis factor-mediated liver diseaseSemantic proximity Read ↗

Hepatic NF-kB-inducing kinase (NIK) suppresses mouse liver regeneration in acute and chronic liver diseasesSemantic proximity Read ↗

Nuclear Factor I-C acts as a regulator of hepatocyte proliferation at the onset of liver regeneration.Semantic proximity Read ↗

Downregulation of the NF-κB protein p65 is a shared phenotype among most anti-aging interventions.Semantic proximity Read ↗

NF-κB essential modifier is required for hepatocyte proliferation and the oval cell reaction after partial hepatectomy in mice.Semantic proximity Read ↗

A novel, dynamic pattern-based analysis of NF-κB binding during the priming phase of liver regeneration reveals switch-like functional regulation of target genesSemantic proximity Read ↗

Transcriptional control of liver regenerationSemantic proximity Read ↗

Mutation in collagen-1 that confers resistance to the action of collagenase results in failure of recovery from CCl4-induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.