Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools.

Human genetics - 1 May 2002

Norton Nadine, Williams Nigel M, Williams Hywel J, Spurlock Gillian, Kirov George, Morris Derek W, Hoogendoorn Bastiaan, Owen Michael J, O'Donovan Michael C

Abstract excerpt

Detecting alleles that confer small increments in susceptibility to disease will require large-scale allelic association studies of single-nucleotide polymorphisms (SNPs) in candidate, or positional candidate, genes. However, current genotyping technologies are one to two orders of magnitude too expensive to permit the analysis of thousands of SNPs in large samples. We have developed and thoroughly validated a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 12073018
DOI: 10.1007/s00439-002-0706-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools.PMID 12073018Read ↗

High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR.Semantic proximity Read ↗

A comparison between SNaPshot, pyrosequencing, and biplex invader SNP genotyping methods: accuracy, cost, and throughput.Semantic proximity Read ↗

Rapid SNP allele frequency determination in genomic DNA pools by pyrosequencing.Semantic proximity Read ↗

Multiplex automated primer extension analysis: simultaneous genotyping of several polymorphisms.Semantic proximity Read ↗

SBE-TAGS: an array-based method for efficient single-nucleotide polymorphism genotyping.Semantic proximity Read ↗

Quantitative determination of allele frequency in pooled DNA by using sequencing method.Semantic proximity Read ↗

Large-scale determination of SNP allele frequencies in DNA pools using MALDI-TOF mass spectrometry.Semantic proximity Read ↗

Single-nucleotide polymorphism genotyping in DNA pools.Semantic proximity Read ↗

A SNaPshot of next generation sequencing for forensic SNP analysis.Semantic proximity Read ↗

Forensic SNP genotyping with SNaPshot: Technical considerations for the development and optimization of multiplexed SNP assays.Semantic proximity Read ↗

Estimation of SNP allele frequencies by SSCP analysis of pooled DNA.Semantic proximity Read ↗

Approaches to allele frequency determination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.