Article
A SNaPshot of next generation sequencing for forensic SNP analysis.
Forensic science international. Genetics - 1 Jan 2015
Daniel R, Santos C, Phillips C, Fondevila M, van Oorschot R A H, Carracedo A, Lareu M V, McNevin D
Abstract excerpt
Forensic phenotyping can provide useful intelligence regarding the biogeographical ancestry (BGA) and externally visible characteristics (EVCs) of the donor of an evidentiary sample. Currently, single nucleotide polymorphism (SNP) based inference of BGA and EVCs is performed most commonly using SNaPshot(®), a single base extension (SBE) assay. However, a single SNaPshot multiplex PCR is limited to 30-40 SNPs....
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