Article
Multiplex automated primer extension analysis: simultaneous genotyping of several polymorphisms.
BioTechniques - 1 Dec 2001
Makridakis N M, Reichardt J K
Abstract excerpt
Accurate and fast genotyping of single nucleotide polymorphisms (SNPs) is of significant scientific importance for linkage and association studies. We report here an automated fluorescent method we call multiplex automated primer extension analysis (MAPA) that can accurately genotype multiple known SNPs simultaneously. This is achieved by substantially improving a commercially available protocol (SNaPshot). This...
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