Article
Rapid SNP allele frequency determination in genomic DNA pools by pyrosequencing.
BioTechniques - 1 May 2002
Neve B, Froguel P, Corset L, Vaillant E, Vatin V, Boutin P
Abstract excerpt
Individual genotyping of single nucleotide polymorphisms (SNPs) remains expensive, especially for linkage disequilibrium mapping strategies involving high-throughput SNP genotyping. On one hand, current methods may suit scientific and laboratory needs in regard to accuracy, reproducibility/robustness, and large-scale application. On the other hand, a cheaper and less time-consuming alternative to individual...
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