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Article

A comparison between SNaPshot, pyrosequencing, and biplex invader SNP genotyping methods: accuracy, cost, and throughput.

Journal of biochemical and biophysical methods - 30 Jul 2004

Pati Nirupma, Schowinsky Valerie, Kokanovic Obrad, Magnuson Victoria, Ghosh Soumitra

Abstract excerpt

Three methods of Single Nucleotide Polymorphism (SNP) detection: SNaPshot, Pyrosequencing and Biplex Invader, with two different chemistries were investigated to compare, (1) accuracy, (2) ease of use, (3) throughput capability, and (4) cost. We genotyped 192 human DNA samples across 24 SNPs (minor allele frequencies above 30%), of which seven SNPs were genotyped with all three methods. We show that the Biplex...

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PMID: 15236905
DOI: 10.1016/j.jbbm.2003.11.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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