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Article

Leukotriene C4 synthase promoter polymorphism in Japanese patients with aspirin-induced asthma.

The Journal of allergy and clinical immunology - 1 Jun 2002

Kawagishi Yukio, Mita Haruhisa, Taniguchi Masami, Maruyama Muneharu, Oosaki Rokuo, Higashi Noritaka, Kashii Tatsuhiko, Kobayashi Masashi, Akiyama Kazuo

Abstract excerpt

BACKGROUND: The A to C transversion in the promoter region of the gene encoding leukotriene C4 synthase (LTC4S) is proposed to be associated with the development of aspirin-induced asthma (AIA). OBJECTIVE: We investigated the frequency of the polymorphism in Japanese population and its association with clinical characteristics and cysteinyl leukotriene production. METHODS: Genotyping of LTC4S gene promoter was...

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Identifiers

PMID: 12063521
DOI: 10.1067/mai.2002.124466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Leukotriene C4 synthase promoter polymorphism in Japanese patients with aspirin-induced asthma.PMID 12063521Read ↗

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