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Article

Leukotriene-related gene polymorphisms in ASA-intolerant asthma: an association with a haplotype of 5-lipoxygenase.

Human genetics - 1 Mar 2004

Choi Jeong-Hee, Park Hae-Sim, Oh Heung-Bum, Lee June-Hyuk, Suh Yu-Jin, Park Choon-Sik, Shin Hyoung-Doo

Abstract excerpt

A recent study has demonstrated the possible involvement of a leukotriene C4 synthase (LTC4S) gene polymorphism in ASA-intolerant asthma (AIA) in a Polish population, whereas no significant association was noted in other populations. To investigate the role of genetic polymorphism in AIA development, we screened single nucleotide polymorphisms (SNPs) of the key enzymes involved in arachidonate metabolism, and the...

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Share to 5-Lipoxygenase-Activating Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14749922
DOI: 10.1007/s00439-004-1082-1

Genes

ALOX5
CYSLTR1
PTGS2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Leukotriene-related gene polymorphisms in ASA-intolerant asthma: an association with a haplotype of 5-lipoxygenase.PMID 14749922Read ↗

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