Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential contribution of the CysLTR1 gene in patients with aspirin hypersensitivity.

Journal of clinical immunology - 1 Nov 2007

Kim Seung-Hyun, Yang Eun-Mi, Park Han-Jung, Ye Young-Min, Lee Hyun-Young, Park Hae-Sim

Abstract excerpt

In this study, we compared the roles of CysLT receptor type 1 (CysLTR1) and leukotriene C4 synthase (LTC4S) gene polymorphisms in two major aspirin-related allergic diseases, aspirin-intolerant asthma (AIA) and aspirin-induced chronic urticaria/angioedema (AICU). CysLTR1-634C>T and LTC4S-444A>C polymorphisms were genotyped and its functional effect on the promoter activity was compared. As in vivo functional...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspirin
Share to Asthma
Share to Diagnosis, Differential

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Hypersensitivity

Share to Glutathione Transferase

Share to Hypersensitivity, Immediate

Share to U937 Cells

Share to Urticaria

Source

Identifiers

PMID: 17641958
DOI: 10.1007/s10875-007-9115-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential contribution of the CysLTR1 gene in patients with aspirin hypersensitivity.PMID 17641958Read ↗

Genetic markers for differentiating aspirin-hypersensitivity.Semantic proximity Read ↗

Cysteinyl leukotriene receptor 1 promoter polymorphism is associated with aspirin-intolerant asthma in males.Semantic proximity Read ↗

CysLTR1 Promoter Polymorphism and Requirement for Leukotriene Receptor Antagonist in Aspirin-Intolerant Asthma PatientsSemantic proximity Read ↗

What do we know about the genetics of aspirin intolerance?Semantic proximity Read ↗

Genetic variability of prostaglandin E2 receptor subtype EP4 gene in aspirin-intolerant chronic urticaria.Semantic proximity Read ↗

Effect of single nucleotide polymorphisms within the interleukin-4 promoter on aspirin intolerance in asthmatics and interleukin-4 promoter activity.Semantic proximity Read ↗

Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics.Semantic proximity Read ↗

The A-444C polymorphism in the leukotriene C4 synthase gene is associated with aspirin-induced urticaria.Semantic proximity Read ↗

Analysis of high-affinity IgE receptor (FcepsilonR1) polymorphisms in patients with aspirin-intolerant chronic urticaria.Semantic proximity Read ↗

Lack of an association between a newly identified promoter polymorphism (-1702G > A) of the leukotriene C4 synthase gene and aspirin-intolerant asthma in a Korean population.Semantic proximity Read ↗

Genetic mechanism of aspirin-induced urticaria/angioedemaSemantic proximity Read ↗

Leukotriene C4 synthase promoter polymorphism in Japanese patients with aspirin-induced asthma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.