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Article

Association analysis of cysteinyl-leukotriene receptor 2 (CYSLTR2) polymorphisms with aspirin intolerance in asthmatics.

Pharmacogenetics and genomics - 1 Jul 2005

Park Jong Sook, Chang Hun Soo, Park Choon-Sik, Lee June-Hyuk, Lee Yong Mok, Choi Jung Hee, Park Hae-Sim, Kim Lyoung Hyo, Park Byung Lae, Choi Yoo Hyun, Shin Hyoung Doo

Abstract excerpt

OBJECTIVES AND METHODS: The cysteinyl leukotriene receptor 2 (CYSLTR2) gene on chromosome 13q14.12-q21.1 encodes a receptor for CYSLTs, potent biological mediators in the pathogenesis of asthma, particularly that associated with aspirin intolerance (AIA). In an effort to discover additional polymorphism(s), the variant(s) of which have been implicated in asthma and aspirin intolerance, we scrutinized genetic...

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Share to Anti-Inflammatory Agents, Non-Steroidal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15970796
DOI: 10.1097/01.fpc.0000166456.84905.a0

Genes

CYSLTR2

Variants

Provenance

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