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Article

Loss of DCC gene expression is of prognostic importance in acute myelogenous leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2002

Inokuchi Koiti, Yamaguchi Hiroki, Hanawa Hideki, Tanosaki Sakae, Nakamura Kayo, Tarusawa Miki, Miyake Koichi, Shimada Takashi, Dan Kazuo

Abstract excerpt

PURPOSE: Expression of the deleted in colorectal carcinoma (DCC) gene has been found to be lost in some patients with acute myelogenous leukemia (AML). Although this finding is critical to leukemogenesis, its prognostic significance remains uncertain. To evaluate this, loss of DCC gene expression in AML patients and their prognostic significance were investigated. EXPERIMENTAL DESIGN: A group of 170 patients with...

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Source

Identifiers

PMID: 12060632

Genes

DCC
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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Loss of DCC gene expression is of prognostic importance in acute myelogenous leukemia.PMID 12060632Read ↗

Alterations in the deleted in colorectal carcinoma gene in human primary leukemia.Semantic proximity Read ↗

The DCC Protein and Prognosis in Colorectal CancerSemantic proximity Read ↗

DCC expression is altered by multiple mechanisms in brain tumours.Semantic proximity Read ↗

Identification of a chromosome 18q gene that is altered in colorectal cancers.Semantic proximity Read ↗

The DCC gene: structural analysis and mutations in colorectal carcinomas.Semantic proximity Read ↗

Analysis of the DCC tumor suppressor gene in testicular germ cell tumors: mutations and loss of expression.Semantic proximity Read ↗

[Structure and function of DCC (deleted in colorectal cancer) gene and its product].Semantic proximity Read ↗

Frequent allelic deletions and loss of expression characterize the DCC gene in male germ cell tumors.Semantic proximity Read ↗

[Loss of heterozygosity involving DCC gene in human colorectal cancers is correlated with the metastatic potential].Semantic proximity Read ↗

Frequent loss of heterozygosity at the deleted in colorectal carcinoma gene locus and its association with histologic phenotypes in breast carcinoma.Semantic proximity Read ↗

Deoxycytidine Kinase (DCK) Mutations in Human Acute Myeloid Leukemia Resistant to Cytarabine.Semantic proximity Read ↗

Frequent loss of expression without sequence mutations of the DCC gene in primary gastric cancer.Semantic proximity Read ↗

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