Article
Association and regulation of casein kinase 2 activity by adenomatous polyposis coli protein.
Proceedings of the National Academy of Sciences of the United States of America - 30 Apr 2002
Homma Miwako Kato, Li Dongxia, Krebs Edwin G, Yuasa Yasuhito, Homma Yoshimi
Abstract excerpt
Mutations in the adenomatous polyposis coli (APC) gene are responsible for familial adenomatous polyposis coli and also sporadic colorectal cancer development. By using antibodies raised against the N-terminal region of APC protein, we have detected the variable masses of endogenous APC proteins in individual cell lines established from human colorectal carcinomas caused by nonsense mutations of the gene....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.