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Article

Novel self-association of the APC molecule affects APC clusters and cell migration.

Journal of cell science - 1 Jun 2008

Li Zhuoyu, Kroboth Karin, Newton Ian P, Näthke Inke S

Abstract excerpt

Truncation mutations in the adenomatous polyposis coli (APC) gene are responsible for familial and sporadic colorectal cancer. APC is a multifunctional protein involved in cell migration, proliferation and differentiation. The APC protein forms specific clusters in the cell periphery that correla...

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Source

Identifiers

PMID: 18477604
DOI: 10.1242/jcs.029470

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18477604-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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