Article
CYP2C19 genotype and S-mephenytoin 4'-hydroxylation phenotype in a Chinese Dai population.
European journal of clinical pharmacology - 1 Apr 2002
He Nan, Yan Feng-Xiang, Huang Song-Lin, Wang Wei, Xiao Zhou-Sheng, Liu Zhao-Qian, Zhou Hong-Hao
Abstract excerpt
AIMS: To investigate the incidence of the CYP2C19 polymorphism in the Chinese Dai population. METHODS: One hundred and ninety-three healthy Chinese Dai volunteers were identified with respect to CYP2C19 by genotype and phenotype analyses. A polymerase chain reaction-restriction fragment length polymorphism method was performed for genotyping procedures. The 4'-hydroxymephenytoin (4'-OH-MP) and S/R-mephenytoin (...
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