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Article

Cyp2c19 genotype and omeprazole hydroxylation phenotype in Chinese Li population.

Clinical and experimental pharmacology & physiology - 1 Jan 2000

Wang Jiu-Hui, Li Pei-Qiong, Fu Qiong-Yao, Li Qiu-Xiang, Cai Wang-Wei

Abstract excerpt

1. CYP2C19 is a polymorphism of cytochrome P450, which is responsible for the metabolism of many drugs. The genetic polymorphism shows interethnic variation and it has been demonstrated that the frequency of poor metabolizers (PM) and the distribution of alleles of CYP2C19 vary among Chinese ethnic nationalities. The aim of the present study was to investigate the incidence of CYP2C19 polymorphism in the Chinese...

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Identifiers

PMID: 17439410
DOI: 10.1111/j.1440-1681.2007.04583.x

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