Article
Genetic variations of S-mephenytoin 4'-hydroxylase (CYP2C19) in the Chinese population.
Life sciences - 25 Feb 2000
Xie H G
Abstract excerpt
Most of phenotyping studies have shown that Chinese populations have a higher incidence of poor metabolizers (PMs) of S-mephenytoin 4'-hydroxylation compared with populations of African and European descent. The present study was aimed at defining an exact population frequency of the genetic defect of S-mephenytoin 4'-hydroxylase (CYP2C19) in native and overseas Chinese healthy populations. All the related data...
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