Article
Differences in the incidence of the CYP2C19 polymorphism affecting the S-mephenytoin phenotype in Chinese Han and Bai populations and identification of a new rare CYP2C19 mutant allele.
The Journal of pharmacology and experimental therapeutics - 1 Apr 1997
Xiao Z S, Goldstein J A, Xie H G, Blaisdell J, Wang W, Jiang C H, Yan F X, He N, Huang S L, Xu Z H, Zhou H H
Abstract excerpt
The incidence of the S-mephenytoin polymorphism was compared in two Chinese ethnic groups, Han (n = 101) and Bai (n = 202) by phenotype and genotype analysis. The frequency of poor metabolizers (PMs) in Han vs. Bai subjects was 19.8% vs. 13.4%. Han subjects had a higher frequency of the mutant CY...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.