Article
Neuromuscular degeneration (nmd): a mutation on mouse chromosome 19 that causes motor neuron degeneration.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 1995
Cook S A, Johnson K R, Bronson R T, Davisson M T
Abstract excerpt
Neuromuscular degeneration, nmd, is a spontaneous autosomal recessive mutation in the mouse producing progressive hindlimb impairment caused by spinal muscular atrophy. We used an intersubspecific intercross between B6.BKs-nmd2J/+ and Mus musculus castaneus (CAST/Ei) to map the nmd mutation to mo...
Topics
- Animals
- Chromosome Mapping
- Ciliary Neurotrophic Factor
- Crosses, Genetic
- Female
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Motor Neurons
- Muscle, Skeletal
- Muscular Atrophy, Spinal
- Mutation
- Nerve Degeneration
- Nerve Growth Factors
- Nerve Tissue Proteins
- Phosphorylases
- Spinal Cord