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Article

Regulation of mast cell phenotype by MITF.

International archives of allergy and immunology - 1 Feb 2002

Kitamura Yukihiko, Morii Eiichi, Jippo Tomoko, Ito Akihiko

Abstract excerpt

The development of mast cells is controlled through the cooperative effects of growth factors and nuclear transcription factors. The signals generated by the binding of stem cell factor (SCF) to c-kit receptor tyrosine kinase (KIT) are essential for their development and survival. A double gene dose of mutant alleles at either the SCF or KIT locus results in a decrease of mast cells. A double gene dose of mutant...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Microphthalmia-Associated Transcription Factor

Share to Proto-Oncogene Proteins c-kit

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Source

Identifiers

PMID: 11919417
DOI: 10.1159/000048178

Genes

MITF
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Regulation of mast cell phenotype by MITF.PMID 11919417Read ↗

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