Article
Analyzing mast cell development and function using mice carrying mutations at W/c-kit or Sl/MGF (SCF) loci.
Annals of the New York Academy of Sciences - 1 Jan 1992
Galli S J, Tsai M, Gordon J R, Geissler E N, Wershil B K
Abstract excerpt
Mast cells have been implicated in a wide variety of biological responses, but identifying the nature and importance of the mast cell's specific contributions to these reactions has been difficult. W/Wv mice have mutations affecting the c-kit tyrosine kinase receptor which is encoded at the W locus and which is necessary for normal mast cell development. In W/Wv mice, the cells which ordinarily give rise to...
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