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Article

Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins.

The Journal of biological chemistry - 14 Jun 2002

von Kobbe Cayetano, Karmakar Parimal, Dawut Lale, Opresko Patricia, Zeng Xianmin, Brosh Robert M, Hickson Ian D, Bohr Vilhelm A

Abstract excerpt

The RecQ helicase family comprises a conserved group of proteins implicated in several aspects of DNA metabolism. Three of the family members are defective in heritable diseases characterized by abnormal growth, premature aging, and predisposition to malignancies. These include the WRN and BLM gene products that are defective in Werner and Bloom syndromes, disorders which share many phenotypic and cellular...

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Share to Adenosine Triphosphatases
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Enzyme-Linked Immunosorbent Assay

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Source

Identifiers

PMID: 11919194
DOI: 10.1074/jbc.M200914200

Genes

WRN
BLM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins.PMID 11919194Read ↗

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